Impaired Learning From Negative Feedback in Stimulant Use Disorder: Dopaminergic Modulation | Zendy

Tsen Vei Lim | Zendy; Rudolf N. Cardinal | Zendy; Edward T. Bullmore | Zendy; Trevor W. Robbins | Zendy; Karen D. Ersche | Zendy

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Impaired Learning From Negative Feedback in Stimulant Use Disorder: Dopaminergic Modulation

Author(s) -

Tsen Vei Lim,

Rudolf N. Cardinal,

Edward T. Bullmore,

Trevor W. Robbins,

Karen D. Ersche

Publication year - 2021

Publication title -

the international journal of neuropsychopharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 107

eISSN - 1469-5111

pISSN - 1461-1457

DOI - 10.1093/ijnp/pyab041

Subject(s) - pramipexole , amisulpride , dopaminergic , dopamine , agonist , psychology , dopamine receptor d3 , stimulant , dopamine receptor d2 , dopamine agonist , pharmacology , neuroscience , medicine , schizophrenia (object oriented programming) , receptor , clozapine , psychiatry , parkinson's disease , disease

Drug-induced alterations to the dopamine system in stimulant use disorder (SUD) are hypothesized to impair reinforcement learning (RL). Computational modeling enables the investigation of the latent processes of RL in SUD patients, which could elucidate the nature of their impairments.

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