Dosage-Dependent Impact of Acute Serotonin Enhancement on Transcranial Direct Current Stimulation Effects | Zendy

Lorena Melo | Zendy; Mohsen Mosayebi-Samani | Zendy; Elham Ghanavati | Zendy; Michael A. Nitsche | Zendy; MinFang Kuo | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Dosage-Dependent Impact of Acute Serotonin Enhancement on Transcranial Direct Current Stimulation Effects

Author(s) -

Lorena Melo,

Mohsen Mosayebi-Samani,

Elham Ghanavati,

Michael A. Nitsche,

MinFang Kuo

Publication year - 2021

Publication title -

the international journal of neuropsychopharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 107

eISSN - 1469-5111

pISSN - 1461-1457

DOI - 10.1093/ijnp/pyab035

Subject(s) - transcranial direct current stimulation , serotonergic , citalopram , neuroplasticity , serotonin , serotonin reuptake inhibitor , psychology , stimulation , antidepressant , neuroscience , medicine , brain stimulation , transcranial magnetic stimulation , reuptake inhibitor , facilitation , receptor , hippocampus

The serotonergic system has an important impact on basic physiological and higher brain functions. Acute and chronic enhancement of serotonin levels via selective serotonin reuptake inhibitor administration impacts neuroplasticity in humans, as shown by its effects on cortical excitability alterations induced by non-invasive brain stimulation, including transcranial direct current stimulation (tDCS). Nevertheless, the interaction between serotonin activation and neuroplasticity is not fully understood, particularly considering dose-dependent effects. Our goal was to explore dosage-dependent effects of acute serotonin enhancement on stimulation-induced plasticity in healthy individuals.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research