Neurons and Astrocytes in Ventrolateral Periaqueductal Gray Contribute to Restraint Water Immersion Stress-Induced Gastric Mucosal Damage via the ERK1/2 Signaling Pathway
Author(s) -
Wenting Gao,
Zepeng Wang,
Hui Wang,
Huimin Li,
Chenxu Huang,
Yangyang Shen,
Xiaoli Ma,
Haiji Sun
Publication year - 2021
Publication title -
the international journal of neuropsychopharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 107
eISSN - 1469-5111
pISSN - 1461-1457
DOI - 10.1093/ijnp/pyab028
Subject(s) - periaqueductal gray , immersion (mathematics) , chemistry , neuroscience , biology , central nervous system , midbrain , mathematics , pure mathematics
The restraint water immersion stress (RWIS) model includes both psychological and physical stimulation, which may lead to gastrointestinal disorders and cause gastric mucosal damage. The ventrolateral periaqueductal gray (VLPAG) contributes to gastrointestinal function, but whether it is involved in RWIS-induced gastric mucosal damage has not yet been reported.
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