Clinical Correlates of the NR3C1 Gene Methylation at Various Stages of Psychosis | Zendy

Błażej Misiak | Zendy; Jerzy Samochowiec | Zendy; Anna Konopka | Zendy; B Gawrońska-Szklarz | Zendy; Jan Aleksander Beszłej | Zendy; Elżbieta Szmida | Zendy; Paweł Karpiński | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Clinical Correlates of the NR3C1 Gene Methylation at Various Stages of Psychosis

Author(s) -

Błażej Misiak,

Jerzy Samochowiec,

Anna Konopka,

B Gawrońska-Szklarz,

Jan Aleksander Beszłej,

Elżbieta Szmida,

Paweł Karpiński

Publication year - 2020

Publication title -

the international journal of neuropsychopharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 107

eISSN - 1469-5111

pISSN - 1461-1457

DOI - 10.1093/ijnp/pyaa094

Subject(s) - psychosis , methylation , gene , psychology , genetics , psychiatry , biology

Dysregulation of epigenetic processes might account for alterations of the hypothalamic-pituitary-adrenal axis observed in patients with schizophrenia. Therefore, in this study, we aimed to investigate methylation of the glucocorticoid receptor (NR3C1) gene in patients with schizophrenia-spectrum disorders, individuals at familial high risk of schizophrenia (FHR-P), and healthy controls with respect to clinical manifestation and a history of psychosocial stressors.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research