Brain Functional Connectivity Correlates of Response in the 7.5% CO2 Inhalational Model of Generalized Anxiety Disorder: A Pilot Study | Zendy

Nathan T. M. Huneke | Zendy; M. John Broulidakis | Zendy; Angela Darekar | Zendy; David S. Baldwin | Zendy; Matthew Garner | Zendy

Open Access

Brain Functional Connectivity Correlates of Response in the 7.5% CO2 Inhalational Model of Generalized Anxiety Disorder: A Pilot Study

Author(s) -

Nathan T. M. Huneke,

M. John Broulidakis,

Angela Darekar,

David S. Baldwin,

Matthew Garner

Publication year - 2020

Publication title -

the international journal of neuropsychopharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 107

eISSN - 1469-5111

pISSN - 1461-1457

DOI - 10.1093/ijnp/pyaa019

Subject(s) - generalized anxiety disorder , functional magnetic resonance imaging , ventromedial prefrontal cortex , functional connectivity , anxiety , amygdala , psychology , valence (chemistry) , prefrontal cortex , audiology , neuroscience , cognition , medicine , psychiatry , physics , quantum mechanics

The 7.5% CO2 inhalational model can be used to explore potential treatments for generalized anxiety disorder. However, it is unknown how inter-individual variability in the functional architecture of negative affective valence systems might relate to anxiogenic response in this model.

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