Disturbance of Oxidative Stress Parameters in Treatment-Resistant Bipolar Disorder and Their Association With Electroconvulsive Therapy Response | Zendy

Qinyu Lv | Zendy; Qiongyue Hu | Zendy; Wenzhong Zhang | Zendy; Xinxin Huang | Zendy; Minghuan Zhu | Zendy; Ruijie Geng | Zendy; Xiaoyan Cheng | Zendy; Chenxi Bao | Zendy; Yingyi Wang | Zendy; Chen Zhang | Zendy; Yongguang He | Zendy; Zezhi Li | Zendy; Zhenghui Yi | Zendy

Open Access

Disturbance of Oxidative Stress Parameters in Treatment-Resistant Bipolar Disorder and Their Association With Electroconvulsive Therapy Response

Author(s) -

Qinyu Lv,

Qiongyue Hu,

Wenzhong Zhang,

Xinxin Huang,

Minghuan Zhu,

Ruijie Geng,

Xiaoyan Cheng,

Chenxi Bao,

Yingyi Wang,

Chen Zhang,

Yongguang He,

Zezhi Li,

Zhenghui Yi

Publication year - 2020

Publication title -

the international journal of neuropsychopharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 107

eISSN - 1469-5111

pISSN - 1461-1457

DOI - 10.1093/ijnp/pyaa003

Subject(s) - young mania rating scale , mania , electroconvulsive therapy , medicine , hamilton rating scale for depression , malondialdehyde , oxidative stress , bipolar disorder , glutathione peroxidase , depression (economics) , psychology , superoxide dismutase , gastroenterology , endocrinology , psychiatry , major depressive disorder , lithium (medication) , electroconvulsive shock , economics , macroeconomics , amygdala

Electroconvulsive therapy (ECT) is an effective option for treatment-resistant bipolar disorder (trBD). However, the mechanisms of its effect are unknown. Oxidative stress is thought to be involved in the underpinnings of BD. Our study is the first, to our knowledge, to report the association between notable oxidative stress parameters (superoxide dismutase [SOD], glutathione peroxidase [GSH-Px], catalase [CAT], and malondialdehyde [MDA]) levels and ECT response in trBD patients.

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