Risk of suicide attempt associated with isotretinoin: a nationwide cohort and nested case-time-control study | Zendy

C. Droitcourt | Zendy; Emmanuel Nowak | Zendy; C. Rault | Zendy; André Happe | Zendy; Béranger Le Nautout | Zendy; Sandrine Kerbrat | Zendy; Frédéric Balusson | Zendy; F. Poizeau | Zendy; D. Travers | Zendy; Jean-Marc Sapori | Zendy; Emmanuel Lagarde | Zendy; Grégoire Rey | Zendy; B. Guillot | Zendy; Emmanuel Oger | Zendy; A. Dupuy | Zendy

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Risk of suicide attempt associated with isotretinoin: a nationwide cohort and nested case-time-control study

Author(s) -

C. Droitcourt,

Emmanuel Nowak,

C. Rault,

André Happe,

Béranger Le Nautout,

Sandrine Kerbrat,

Frédéric Balusson,

F. Poizeau,

D. Travers,

Jean-Marc Sapori,

Emmanuel Lagarde,

Grégoire Rey,

B. Guillot,

Emmanuel Oger,

A. Dupuy

Publication year - 2019

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyz093

Subject(s) - isotretinoin , medicine , interquartile range , nested case control study , incidence (geometry) , cohort study , population , cohort , confidence interval , poison control , pediatrics , acne , demography , emergency medicine , environmental health , dermatology , physics , sociology , optics

Isotretinoin is the only effective treatment for severe acne. An isotretinoin-related suicide risk is still debated and under scrutiny by regulatory agencies. Our objectives were: to assess the risk of suicide attempt before, during and after isotretinoin treatment; to detect any potential triggering effect of isotretinoin initiation on suicide attempt.

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