Physical activity, mediating factors and risk of colon cancer: insights into adiposity and circulating biomarkers from the EPIC cohort | Zendy

Krasimira Aleksandrova | Zendy; Mazda Jenab | Zendy; Michael F. Leitzmann | Zendy; Bas BuenodeMesquita | Zendy; Rudolf Kaaks | Zendy; Antonia Trichopoulou | Zendy; Christina Bamia | Zendy; Παγώνα Λάγιου | Zendy; Sabina Rinaldi | Zendy; Heinz Freisling | Zendy; Marion Carayol | Zendy; Tobias Pischon | Zendy; Dagmar Drogan | Zendy; Elisabete Weiderpass | Zendy; Paula Jakszyn | Zendy; Kim Overvad | Zendy; Christina C. Dahm | Zendy; Anne Tjønneland | Zendy; Marie-Christine Bouton-Ruault | Zendy; Tilman Kühn | Zendy; Eleni Peppa | Zendy; Elisavet Valanou | Zendy; Carlo La Vecchia | Zendy; Domenico Palli | Zendy; Salvatore Panico | Zendy; Carlotta Sacerdote | Zendy; Claudia Agnoli | Zendy; ­Rosario ­Tumino | Zendy; Anne M. May | Zendy; Jonna van Vulpen | Zendy; Kristin Benjaminsen Borch | Zendy; Sunday Oluwafemi Oyeyemi | Zendy; J. Ramón Quirós | Zendy; Catalina Bonet | Zendy; MaríaJosé Sánchez | Zendy; Miren Dorronsoro | Zendy; Carmen Navarro | Zendy; Aurelio Barricarte | Zendy; Bethany Van Guelpen | Zendy; Patrik Wennberg | Zendy; Timothy J. Key | Zendy; KayTee Khaw | Zendy; Nicholas J. Wareham | Zendy; Nada Assi | Zendy; Heather Ward | Zendy; Dagfinn Aune | Zendy; Elio Ríboli | Zendy; Heiner Boeing | Zendy

Open Access

Physical activity, mediating factors and risk of colon cancer: insights into adiposity and circulating biomarkers from the EPIC cohort

Author(s) -

Krasimira Aleksandrova,

Mazda Jenab,

Michael F. Leitzmann,

Bas BuenodeMesquita,

Rudolf Kaaks,

Antonia Trichopoulou,

Christina Bamia,

Παγώνα Λάγιου,

Sabina Rinaldi,

Heinz Freisling,

Marion Carayol,

Tobias Pischon,

Dagmar Drogan,

Elisabete Weiderpass,

Paula Jakszyn,

Kim Overvad,

Christina C. Dahm,

Anne Tjønneland,

Marie-Christine Bouton-Ruault,

Tilman Kühn,

Eleni Peppa,

Elisavet Valanou,

Carlo La Vecchia,

Domenico Palli,

Salvatore Panico,

Carlotta Sacerdote,

Claudia Agnoli,

Rosario Tumino,

Anne M. May,

Jonna van Vulpen,

Kristin Benjaminsen Borch,

Sunday Oluwafemi Oyeyemi,

J. Ramón Quirós,

Catalina Bonet,

MaríaJosé Sánchez,

Miren Dorronsoro,

Carmen Navarro,

Aurelio Barricarte,

Bethany Van Guelpen,

Patrik Wennberg,

Timothy J. Key,

KayTee Khaw,

Nicholas J. Wareham,

Nada Assi,

Heather Ward,

Dagfinn Aune,

Elio Ríboli,

Heiner Boeing

Publication year - 2017

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyx174

Subject(s) - medicine , waist , european prospective investigation into cancer and nutrition , colorectal cancer , cohort , body mass index , cancer , confidence interval , cohort study , leptin , diet and cancer , anthropometry , oncology , endocrinology , obesity

There is convincing evidence that high physical activity lowers the risk of colon cancer; however, the underlying biological mechanisms remain largely unknown. We aimed to determine the extent to which body fatness and biomarkers of various biologically plausible pathways account for the association between physical activity and colon cancer.

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