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Family aggregation of cardiovascular disease mortality: a register-based prospective study of pooled Nordic twin cohorts
Author(s) -
Karri Silventoinen,
Jacob Hjelmborg,
Sören Möller,
Samuli Ripatti,
Axel Skythe,
Emmi Tikkanen,
Nancy L. Pedersen,
Patrik K. E. Magnusson,
Kaare Christensen,
Jaakko Kaprio
Publication year - 2017
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyx012
Subject(s) - medicine , stroke (engine) , relative risk , family aggregation , dizygotic twin , twin study , confidence interval , demography , disease , risk factor , cause of death , prospective cohort study , hazard ratio , epidemiology , pediatrics , heritability , genetics , mechanical engineering , sociology , biology , engineering
Familial factors play an important role in the variation of risk factors of cardiovascular diseases (CVD), but less is known about how they affect the risk of death from CVD. We estimated familial aggregation of CVD mortality for twins offering the maximum level of risk due to genetic and other familial factors.

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