Perinatal microbial exposure may influence aortic intima-media thickness in early infancy | Zendy

Kate McCloskey | Zendy; Peter Vuillermin | Zendy; John B. Carlin | Zendy; Michael Cheung | Zendy; Michael R. Skilton | Zendy; Mimi L.K. Tang | Zendy; Katrina J. Allen | Zendy; Gwendolyn L. Gilbert | Zendy; Sarath Ranganathan | Zendy; Fiona Collier | Zendy; Terence Dwyer | Zendy; Anne–Louise Ponsonby | Zendy; David Burgner | Zendy

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Perinatal microbial exposure may influence aortic intima-media thickness in early infancy

Author(s) -

Kate McCloskey,

Peter Vuillermin,

John B. Carlin,

Michael Cheung,

Michael R. Skilton,

Mimi L.K. Tang,

Katrina J. Allen,

Gwendolyn L. Gilbert,

Sarath Ranganathan,

Fiona Collier,

Terence Dwyer,

Anne–Louise Ponsonby,

David Burgner

Publication year - 2016

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyw042

Subject(s) - medicine , obstetrics , pregnancy , gestation , population , gestational age , body mass index , caesarean section , gestational diabetes , pediatrics , environmental health , biology , genetics

The maternal and infant microbiome may influence infant cardiovascular risk through immune programming. The maternal vagino-enteric microbiome is often sampled for group B streptococcus (GBS) colonization during pregnancy. Our aim was to investigate the association between maternal GBS colonization, intrapartum antibiotics, antenatal pet exposure and infant aortic intima-media thickness (aIMT), an intermediate vascular phenotype, and whether this association varied by mode of delivery.

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