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Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome
Author(s) -
Rowena Chau,
S. Ghazaleh Dashti,
Driss Ait Ouakrim,
Daniel D. Buchanan,
Mark Clendenning,
Christophe Rosty,
Ingrid Winship,
Joanne Young,
Graham G. Giles,
Finlay Macrae,
Alex Boussioutas,
Susan Parry,
Jane C. Figueiredo,
A. Joan Levine,
Dennis J. Ahnen,
Graham Casey,
Robert W. Haile,
Steven Gallinger,
Loı̈c Le Marchand,
Stephen N. Thibodeau,
Noralane M. Lindor,
Polly A. Newcomb,
John D. Potter,
John A. Baron,
John L. Hopper,
Mark A. Jenkins,
Aung Ko Win
Publication year - 2016
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyw036
Subject(s) - multivitamin , medicine , colorectal cancer , hazard ratio , lynch syndrome , confounding , lower risk , cancer , confidence interval , vitamin , dna mismatch repair
People with a DNA mismatch repair (MMR) gene mutation have a substantially elevated risk of colorectal cancer (CRC) but the modifiers of this risk are not well established. We investigated the association between dietary supplement intake and CRC risk for carriers.

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