Zinc intake and risk of Crohn’s disease and ulcerative colitis: a prospective cohort study
Author(s) -
Ashwin N. Ananthakrishnan,
Hamed Khalili,
Mingyang Song,
Leslie M. Higuchi,
James M. Richter,
Andrew T. Chan
Publication year - 2015
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyv301
Subject(s) - medicine , hazard ratio , ulcerative colitis , prospective cohort study , crohn's disease , confidence interval , confounding , proportional hazards model , cohort study , inflammatory bowel disease , gastroenterology , zinc , disease , lower risk , epidemiology , relative risk , materials science , metallurgy
Diet plays a role in the pathogenesis of Crohn’s disease (CD) and ulcerative colitis (UC). Dietary zinc may influence risk of disease through effects on autophagy, innate and adaptive immune response and maintenance of the intestinal barrier.
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