Continuous decline in mortality from coronary heart disease in Japan despite a continuous and marked rise in total cholesterol: Japanese experience after the Seven Countries Study
Author(s) -
Akira Sekikawa,
Yoshihiro Miyamoto,
Katsuyuki Miura,
Kunihiro Nishimura,
Bradley J. Willcox,
Kamal Masaki,
Beatriz L. Rodríguez,
Russell P. Tracy,
Tomonori Okamura,
Lewis H. Kuller
Publication year - 2015
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyv143
Subject(s) - medicine , demography , coronary heart disease , mortality rate , cohort study , cohort , epidemiology , total cholesterol , cholesterol , sociology
The Seven Countries Study in the 1960s showed very low mortality from coronary heart disease (CHD) in Japan, which was attributed to very low levels of total cholesterol. Studies of migrant Japanese to the USA in the 1970s documented increase in CHD rates, thus CHD mortality in Japan was expected to increase as their lifestyle became Westernized, yet CHD mortality has continued to decline since 1970. This study describes trends in CHD mortality and its risk factors since 1980 in Japan, contrasting those in other selected developed countries.
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