Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium
Author(s) -
Dmitry Shungin,
M. C. Cornelis,
Kimon Divaris,
B. Holtfreter,
John R. Shaffer,
YauHua Yu,
S. P. Barros,
J. D. Beck,
R. Biffar,
Eric Boerwinkle,
R. J. Crout,
Andrea Ganna,
G. Hallmans,
George Hindy,
Joshua Shulman,
Peter Kraft,
D. W. McNeil,
Olle Melander,
K. L. Moss,
Kari E. North,
Marju OrhoMelander,
Nancy L. Pedersen,
Paul M. Ridker,
Eric B. Rimm,
Lynda M. Rose,
Gull Rukh,
Alexander Teumer,
Robert J. Weyant,
Daniel I. Chasman,
Kaumudi Joshipura,
Thomas Kocher,
Patrik K. E. Magnusson,
Mary L. Marazita,
P.M. Nilsson,
Steven Offenbacher,
George Davey Smith,
Pernilla Lundberg,
Tom Palmer,
Nicholas J. Timpson,
Ingegerd Johansson,
Paul W. Franks
Publication year - 2015
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyv075
Subject(s) - mendelian randomization , periodontitis , medicine , odds ratio , confounding , confidence interval , observational study , body mass index , meta analysis , genotype , genetics , biology , genetic variants , gene
The observational relationship between obesity and periodontitis is widely known, yet causal evidence is lacking. Our objective was to investigate causal associations between periodontitis and body mass index (BMI).
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