Common genetic variants in epigenetic machinery genes and risk of upper gastrointestinal cancers
Author(s) -
Hyuna Sung,
Howard H. Yang,
Han Zhang,
Qi Yang,
Nan Hu,
Ze-Zhong Tang,
Hua Su,
Lemin Wang,
Chaoyu Wang,
Ti Ding,
JinHu Fan,
YouLin Qiao,
William Wheeler,
Carol Giffen,
Laurie Burdett,
Zhaoming Wang,
Maxwell P. Lee,
Stephen J. Chanock,
Sanford M. Dawsey,
Neal D. Freedman,
Christian C. Abnet,
Alisa M. Goldstein,
Kai Yu,
Philip R. Taylor,
Paula L. Hyland
Publication year - 2015
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyv050
Subject(s) - epigenetics , biology , expression quantitative trait loci , genetics , dna methylation , microrna , hox gene , gene , chromatin remodeling , chromatin , histone , quantitative trait locus , cancer , bioinformatics , gene expression , single nucleotide polymorphism , genotype
Populations in north central China are at high risk for oesophageal squamous cell carcinoma (ESCC) and gastric cancer (GC), and genetic variation in epigenetic machinery genes and pathways may contribute to this risk.
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