Maternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: findings from the Avon Longitudinal Study of Parents and Children | Zendy

Gemma C. Sharp | Zendy; Debbie A. Lawlor | Zendy; Rebecca C. Richmond | Zendy; Abigail Fraser | Zendy; Andrew J. Simpkin | Zendy; Matthew Suderman | Zendy; Hashem A. Shihab | Zendy; Oliver Lyttleton | Zendy; Wendy L. McArdle | Zendy; Susan M. Ring | Zendy; Tom R. Gaunt | Zendy; George Davey Smith | Zendy; Caroline L. Relton | Zendy

Open Access

Maternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: findings from the Avon Longitudinal Study of Parents and Children

Author(s) -

Gemma C. Sharp,

Debbie A. Lawlor,

Rebecca C. Richmond,

Abigail Fraser,

Andrew J. Simpkin,

Matthew Suderman,

Hashem A. Shihab,

Oliver Lyttleton,

Wendy L. McArdle,

Susan M. Ring,

Tom R. Gaunt,

George Davey Smith,

Caroline L. Relton

Publication year - 2015

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyv042

Subject(s) - offspring , underweight , body mass index , obesity , dna methylation , pregnancy , epigenome , medicine , endocrinology , biology , physiology , overweight , genetics , gene expression , gene

Evidence suggests that in utero exposure to undernutrition and overnutrition might affect adiposity in later life. Epigenetic modification is suggested as a plausible mediating mechanism.

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