Using linked educational attainment data to reduce bias due to missing outcome data in estimates of the association between the duration of breastfeeding and IQ at 15 years
Author(s) -
Rosie Cornish,
Kate Tilling,
Andy Boyd,
Amy Davies,
John Macleod
Publication year - 2015
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyv035
Subject(s) - missing data , breastfeeding , proxy (statistics) , imputation (statistics) , educational attainment , linkage (software) , demography , association (psychology) , psychology , intelligence quotient , record linkage , medicine , statistics , population , pediatrics , environmental health , mathematics , psychiatry , cognition , biochemistry , chemistry , sociology , economics , psychotherapist , gene , economic growth
Most epidemiological studies have missing information, leading to reduced power and potential bias. Estimates of exposure-outcome associations will generally be biased if the outcome variable is missing not at random (MNAR). Linkage to administrative data containing a proxy for the missing study outcome allows assessment of whether this outcome is MNAR and the evaluation of bias. We examined this in relation to the association between infant breastfeeding and IQ at 15 years, where a proxy for IQ was available through linkage to school attainment data.
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