Adiposity is associated with DNA methylation profile in adipose tissue | Zendy

Golareh Agha | Zendy; E. Andrés Houseman | Zendy; Karl T. Kelsey | Zendy; Charles B. Eaton | Zendy; Stephen L. Buka | Zendy; Eric B. Loucks | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Adiposity is associated with DNA methylation profile in adipose tissue

Author(s) -

Golareh Agha,

E. Andrés Houseman,

Karl T. Kelsey,

Charles B. Eaton,

Stephen L. Buka,

Eric B. Loucks

Publication year - 2014

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyu236

Subject(s) - dna methylation , adipose tissue , methylation , medicine , dna , endocrinology , biology , bioinformatics , genetics , gene , gene expression

Adiposity is a risk factor for type 2 diabetes and cardiovascular disease, suggesting an important role for adipose tissue in the development of these conditions. The epigenetic underpinnings of adiposity are not well understood, and studies of DNA methylation in relation to adiposity have rarely focused on target adipose tissue. Objectives were to evaluate whether genome-wide DNA methylation profiles in subcutaneous adipose tissue and peripheral blood leukocytes are associated with measures of adiposity, including central fat mass, body fat distribution and body mass index.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research