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Increased carriage of macrolide-resistant fecalE. colifollowing mass distribution of azithromycin for trachoma control
Author(s) -
Jessica C. Seidman,
Christian Coles,
Ellen K. Silbergeld,
Joshua Levens,
Harran Mkocha,
Lashaunda B. Johnson,
Beatriz Muñoz,
Sheila K. West
Publication year - 2014
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyu062
Subject(s) - azithromycin , trachoma , medicine , carriage , feces , veterinary medicine , drug resistance , microbiology and biotechnology , antibiotics , biology , pathology
Mass drug treatment with azithromycin (MDA) is part of the WHO-endorsed 'SAFE' strategy for trachoma control in endemic communities. MDA has been associated with reduced trachoma prevalence and short-term reductions in other bacterial infections, but can also lead to increased circulation of macrolide-resistant bacteria.

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