Effects of study precision and risk of bias in networks of interventions: a network meta-epidemiological study | Zendy

Anna Chaimani | Zendy; Haris S. Vasiliadis | Zendy; Nikolaos Pandis | Zendy; Christopher H. Schmid | Zendy; Nicky J. Welton | Zendy; Georgia Salanti | Zendy

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Effects of study precision and risk of bias in networks of interventions: a network meta-epidemiological study

Author(s) -

Anna Chaimani,

Haris S. Vasiliadis,

Nikolaos Pandis,

Christopher H. Schmid,

Nicky J. Welton,

Georgia Salanti

Publication year - 2013

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyt074

Subject(s) - meta analysis , blinding , sample size determination , random effects model , statistics , medicine , variance (accounting) , meta regression , odds ratio , publication bias , randomized controlled trial , study heterogeneity , econometrics , mathematics , accounting , business

Empirical research has illustrated an association between study size and relative treatment effects, but conclusions have been inconsistent about the association of study size with the risk of bias items. Small studies give generally imprecisely estimated treatment effects, and study variance can serve as a surrogate for study size.

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