Open AccessIs aldehyde dehydrogenase 2 a credible genetic instrument for alcohol use in Mendelian randomization analysis in Southern Chinese men?
Author(s) -
Shiu Lun Au Yeung,
Chao Jiang,
Kar Keung Cheng,
Bohong Liu,
Weizhen Zhang,
TH Lam,
GM Leung,
C. Mary Schooling
Publication year - 2012
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dys221
Subject(s) - aldh2 , mendelian randomization , medicine , genetics , allele , biology , genotype , genetic variants , gene
Mendelian randomization studies provide a means of assessing causal relations without interventions, but require valid genetic instruments. We assessed the credibility of aldehyde dehydrogenase 2 (ALDH2) as a genetic instrument for alcohol use in Southern Chinese men.
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