Association between blood pressure and DNA methylation of retrotransposons and pro-inflammatory genes | Zendy

Stacey E. Alexeeff | Zendy; Andrea Baccarelli | Zendy; Jaana I. Halonen | Zendy; Brent A. Coull | Zendy; Robert O. Wright | Zendy; Letizia Tarantini | Zendy; Valentina Bollati | Zendy; David Sparrow | Zendy; P. Vokonas | Zendy; Joel Schwartz | Zendy

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Association between blood pressure and DNA methylation of retrotransposons and pro-inflammatory genes

Author(s) -

Stacey E. Alexeeff,

Andrea Baccarelli,

Jaana I. Halonen,

Brent A. Coull,

Robert O. Wright,

Letizia Tarantini,

Valentina Bollati,

David Sparrow,

P. Vokonas,

Joel Schwartz

Publication year - 2013

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dys220

Subject(s) - dna methylation , methylation , epigenetics , biology , genetics , gene , retrotransposon , gene expression , genome , transposable element

Methylation of deoxyribonucleic acid (DNA) is an epigenetic regulator of gene expression that changes with age, but its contribution to aging-related disorders, including high blood pressure (BP), is still largely unknown. We examined the relation of BP to the methylation of retrotransposon sequences of DNA and of selected candidate genes.

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