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Osteoprotegerin is associated with hip fracture incidence: the Tromso Study
Author(s) -
Lone Jørgensen,
JohnBjarne Hansen,
Luai A. Ahmed,
Åshild Bjørnerem,
Nina Emaus,
Ragnar M. Joakimsen,
E. B. Mathiesen,
Jan Störmer,
Anders Vik,
Bjarne K. Jacobsen
Publication year - 2012
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dys063
Subject(s) - medicine , quartile , osteoprotegerin , hip fracture , incidence (geometry) , confounding , confidence interval , population , bone resorption , osteoporosis , endocrinology , environmental health , physics , receptor , activator (genetics) , optics
Osteoprotegerin (OPG) is a cytokine essential for the regulation of bone resorption, but large longitudinal studies on its relationship to fracture risk in humans are lacking. In this population-based study of 2740 men and 2857 post-menopausal women, it was examined whether serum OPG was associated with hip fracture incidence. The participants were followed for 15 years.

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