Smallpox vaccination and all-cause infectious disease hospitalization: a Danish register-based cohort study | Zendy

Signe Sørup | Zendy; Marie Villumsen | Zendy; Henrik Ravn | Zendy; Christine Stabell Benn | Zendy; Grith Lykke Sørensen | Zendy; Peter Aaby | Zendy; Tine Jess | Zendy; Adam Roth | Zendy

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Smallpox vaccination and all-cause infectious disease hospitalization: a Danish register-based cohort study

Author(s) -

Signe Sørup,

Marie Villumsen,

Henrik Ravn,

Christine Stabell Benn,

Grith Lykke Sørensen,

Peter Aaby,

Tine Jess,

Adam Roth

Publication year - 2011

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyr063

Subject(s) - medicine , danish , smallpox , vaccination , epidemiology , infectious disease (medical specialty) , cohort study , pediatrics , cohort , smallpox vaccine , virology , disease , vaccinia , biology , biochemistry , gene , recombinant dna , philosophy , linguistics

There is growing evidence from observational studies and randomized trials in low-income countries that vaccinations have non-specific effects. Administration of live vaccines reduces overall child morbidity and mortality, presumably due to protection against non-targeted infections. In Denmark, the live vaccine against smallpox was phased out in the 1970s due to the eradication of smallpox. We used the phasing-out period to investigate the effect of smallpox vaccination on the risk of hospitalization for infections.

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