Cortisol, estrogens and risk of ischaemic heart disease, cancer and all-cause mortality in postmenopausal women: a prospective cohort study
Author(s) -
Naja Hulvej Rod,
Thomas Kristensen,
Finn Diderichsen,
Eva Prescott,
Gorm Boje Jensen,
Åse Marie Hansen
Publication year - 2009
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyp354
Subject(s) - medicine , prospective cohort study , ischaemic heart disease , biomarker , hormone , cancer , cohort study , disease , estrogen , cohort , postmenopausal women , endocrinology , physiology , oncology , biochemistry , chemistry
Chronic stress may affect morbidity and mortality through neuroendocrine changes, and the ratio of cortisol to sex steroid hormones has been suggested as a biomarker of stress. We aim to address a relation between the ratio of cortisol to estrogens (C/E) and risk of ischaemic heart disease (IHD), hormone-dependent cancers and all-cause mortality among postmenopausal women.
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