Influences on the reduction of relative telomere length over 10 years in the population-based Bruneck Study: introduction of a well-controlled high-throughput assay | Zendy

Silvia Ehrlenbach | Zendy; Peter Willeit | Zendy; Stefan Kiechl | Zendy; Johann Willeit | Zendy; Markus Reindl | Zendy; Kathrin Schanda | Zendy; Florian Kronenberg | Zendy; Anita KlossBrandstätter | Zendy

Open Access

Influences on the reduction of relative telomere length over 10 years in the population-based Bruneck Study: introduction of a well-controlled high-throughput assay

Author(s) -

Silvia Ehrlenbach,

Peter Willeit,

Stefan Kiechl,

Johann Willeit,

Markus Reindl,

Kathrin Schanda,

Florian Kronenberg,

Anita KlossBrandstätter

Publication year - 2009

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyp273

Subject(s) - telomere , population , medicine , biology , oncology , genetics , dna , environmental health

Telomeres play a key role in the maintenance of chromosome integrity. Short telomeres are linked to age-associated diseases and cancer. Our aim was to determine the decrease rate of relative telomere length (RTL) over 10 years and whether this rate was influenced by age, sex and smoking behaviour.

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