Obesity and cancer: Mendelian randomization approach utilizing the FTO genotype
Author(s) -
Paul Brennan,
James McKay,
Lee E. Moore,
D. Zaridze,
Anush Mukeria,
Neonila SzeszeniaDąbrowska,
Jolanta Lissowska,
P. Rudnai,
Eleonóra Fabiánová,
Dana Mateș,
Vladimír Bencko,
Lenka Foretová,
Vladimír Janout,
WongHo Chow,
Nathanial Rothman,
Amélie Chabrier,
V. Gaborieau,
Nicholas J. Timpson,
Rayjean J. Hung,
George Davey Smith
Publication year - 2009
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyp162
Subject(s) - mendelian randomization , medicine , odds ratio , obesity , confounding , confidence interval , genotype , cancer , lung cancer , oncology , allele , body mass index , bioinformatics , genetics , biology , gene , genetic variants
Obesity is a risk factor for several cancers although appears to have an inverse association with cancers strongly related to tobacco. Studying obesity is difficult due to numerous biases and confounding.
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