Interpreting data in the face of competing explanations: assessing the hypothesis that observed spontaneous clearance of Helicobacter pylori was all measurement error | Zendy

Carl V. Phillips | Zendy; Karen J. Goodman | Zendy

Open Access

Interpreting data in the face of competing explanations: assessing the hypothesis that observed spontaneous clearance of Helicobacter pylori was all measurement error

Author(s) -

Carl V. Phillips,

Karen J. Goodman

Publication year - 2009

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyp006

Subject(s) - helicobacter pylori , false positive paradox , helicobacter pylori infection , medicine , cohort , transient (computer programming) , artifact (error) , psychology , statistics , mathematics , computer science , operating system , neuroscience

We previously reported frequent transient positive urea breath tests for Helicobacter pylori infection in a cohort study of young children, and interpreted this as evidence of frequent spontaneous clearance of this infection. In a commentary, Perry and Parsonnet suggested that all transient positive tests we observed could be false positives and thus the appearance of transient infection could be an artifact.

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