Space-time analysis of Down syndrome: results consistent with transient pre-disposing contagious agent | Zendy

Richard McNally | Zendy; Judith Rankin | Zendy; Mark Shirley | Zendy; Steven Rushton | Zendy; Tanja PlessMulloli | Zendy

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Space-time analysis of Down syndrome: results consistent with transient pre-disposing contagious agent

Author(s) -

Richard McNally,

Judith Rankin,

Mark Shirley,

Steven Rushton,

Tanja PlessMulloli

Publication year - 2008

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyn083

Subject(s) - trisomy , cluster analysis , down syndrome , population , etiology , medicine , pediatrics , statistics , biology , genetics , mathematics , environmental health , psychiatry

Whilst maternal age is an established risk factor for Patau syndrome (trisomy 13), Edwards syndrome (trisomy 18) and Down syndrome (trisomy 21), the aetiology and contribution of genetic and environmental factors remains unclear. We analysed for space-time clustering using high quality fully population-based data from a geographically defined region.

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