The impact of community level treatment and preventative interventions on trachoma prevalence in rural Ethiopia | Zendy

Phillippa Cumberland | Zendy; Tansy Edwards | Zendy; Girma Hailu | Zendy; Emma M. HardingEsch | Zendy; Anne Helms Andreasen | Zendy; David Mabey | Zendy; Jim Todd | Zendy

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The impact of community level treatment and preventative interventions on trachoma prevalence in rural Ethiopia

Author(s) -

Phillippa Cumberland,

Tansy Edwards,

Girma Hailu,

Emma M. HardingEsch,

Anne Helms Andreasen,

David Mabey,

Jim Todd

Publication year - 2008

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyn045

Subject(s) - trachoma , medicine , azithromycin , chlamydia trachomatis , psychological intervention , public health , mass drug administration , environmental health , odds ratio , chlamydia , antibiotics , population , gynecology , immunology , pathology , biology , nursing , microbiology and biotechnology

The International Trachoma Initiative (ITI) trachoma control programme based on the SAFE strategy (Surgery, Antibiotics, Facial cleanliness and Environmental improvement) was implemented in 2002 in two rural Ethiopian zones, with mass delivery of azithromycin starting in 2003. We evaluate the impact of combined antibiotic and health educational interventions on active trachoma and Chlamydia trachomatis detected from ocular swabs, in children aged 3-9 years. Method Three-year follow-up cross-sectional survey was carried out in 40 rural Ethiopian communities to evaluate the programme. Households were randomly selected and all children were invited for eye examination for active trachoma. In 2005, eye swabs were taken for Polymerase Chain Reaction (PCR) detection of ocular C. trachomatis DNA. Adult knowledge and behaviour related to trachoma were assessed.

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