Designing and implementing a large-scale automated -80 C archive | Zendy

Owen Jones | Zendy; P. J. Woods | Zendy

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Designing and implementing a large-scale automated -80 C archive

Author(s) -

Owen Jones,

P. J. Woods

Publication year - 2008

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dym293

Subject(s) - biobank , computer science , refrigerant , liquid nitrogen , sample (material) , scale (ratio) , database , process engineering , environmental science , engineering , chemistry , bioinformatics , mechanical engineering , biology , chromatography , organic chemistry , gas compressor , physics , quantum mechanics

This article describes an automated facility for storing biological samples at -80 degrees C, designed to meet the needs of The UK Biobank. No store of this size has previously used liquid nitrogen as refrigerant, and so it was important to confirm the storage compartments could achieve and maintain uniform conditions with efficient use of the coolant. In addition, the store incorporates a novel system of drawers designed to allow robotic access whilst maintaining storage conditions. Experiments were undertaken to prove the performance of both these factors in maintaining the temperature of stored samples, both in steady-state conditions and during sample access.

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