Investigating gene–environment interaction in complex diseases: increasing power by selective sampling for environmental exposure | Zendy

Marco P. Boks | Zendy; Maria Schipper | Zendy; Chris D. Schubart | Zendy; Iris E. Sommer | Zendy; René S. Kahn | Zendy; Roel A. Ophoff | Zendy

Open Access

Investigating gene–environment interaction in complex diseases: increasing power by selective sampling for environmental exposure

Author(s) -

Marco P. Boks,

Maria Schipper,

Chris D. Schubart,

Iris E. Sommer,

René S. Kahn,

Roel A. Ophoff

Publication year - 2007

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dym215

Subject(s) - genotyping , sampling (signal processing) , gene–environment interaction , genotype , computational biology , biology , gene , genetics , computer science , filter (signal processing) , computer vision

The often limited influence of disease associated alleles on the vulnerability to complex diseases has lead to increased interest in environmental interaction with genotype. However, gene environmental interactions (GEIs) are not easily studied, since high numbers of subjects are required to detect GEI.

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