Commentary: Low dose-rate exposures to ionizing radiation
Author(s) -
Elisabeth Cardis
Publication year - 2007
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dym192
Subject(s) - ionizing radiation , confidence interval , medicine , demography , cancer incidence , relative risk , nuclear medicine , cohort , population , cancer , incidence (geometry) , attributable risk , environmental health , irradiation , mathematics , physics , nuclear physics , geometry , sociology
who reside in the catchment area of the Chelyabisnk regional oncology centre. The analyses are based on over 47 years of follow-up and over 1800 cases of cancer. They report a significant radiation-related increase in solid cancer incidence in this population (with about 3% of the cancer cases attributable to radiation). The estimated excess relative risk (ERR) of solid cancer is 1.0/Gy of radiation dose [95% confidence interval (CI) 0.3, 1.9], very similar to the estimate these authors obtained based on cancer mortality in the entire expanded Techa River Cohort 8 (Table 1). These estimates are higher than, though statistically compatible with, comparable estimates derived by extrapolation from the atomic bomb survivors study (gender-averaged ERR estimate at age 65
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