Impact of allocation concealment on conclusions drawn from meta-analyses of randomized trials
Author(s) -
Julie Pildal,
Asbjørn Hróbjartsson,
Karsten Juhl Jørgensen,
Jørgen Hilden,
Douglas G. Altman,
Peter C Gøtzsche
Publication year - 2007
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dym087
Subject(s) - randomized controlled trial , meta analysis , psychological intervention , robustness (evolution) , medicine , psychiatry , surgery , pathology , biochemistry , chemistry , gene
Randomized trials without reported adequate allocation concealment have been shown to overestimate the benefit of experimental interventions. We investigated the robustness of conclusions drawn from meta-analyses to exclusion of such trials.
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