Sample size for cluster randomized trials: effect of coefficient of variation of cluster size and analysis method | Zendy

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Sample size for cluster randomized trials: effect of coefficient of variation of cluster size and analysis method

Author(s) -

Sandra Eldridge,

Deborah Ashby,

Sally Kerry

Publication year - 2006

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyl129

Subject(s) - sample size determination , cluster (spacecraft) , randomized controlled trial , cluster randomised controlled trial , statistics , cluster size , sample (material) , medicine , computer science , mathematics , physics , programming language , electronic structure , quantum mechanics , thermodynamics

Cluster randomized trials are increasingly popular. In many of these trials, cluster sizes are unequal. This can affect trial power, but standard sample size formulae for these trials ignore this. Previous studies addressing this issue have mostly focused on continuous outcomes or methods that are sometimes difficult to use in practice.

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