Association of cytokine and DNA repair gene polymorphisms with hepatitis B-related hepatocellular carcinoma | Zendy

ChunChieh Chen | Zendy; ShiYi Yang | Zendy; ChunJen Liu | Zendy; ChihLin Lin | Zendy; YunFan Liaw | Zendy; ShiMing Lin | Zendy; ShouDong Lee | Zendy; PeiJer Chen | Zendy; ChienJen Chen | Zendy; MingWhei Yu | Zendy

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Association of cytokine and DNA repair gene polymorphisms with hepatitis B-related hepatocellular carcinoma

Author(s) -

ChunChieh Chen,

ShiYi Yang,

ChunJen Liu,

ChihLin Lin,

YunFan Liaw,

ShiMing Lin,

ShouDong Lee,

PeiJer Chen,

ChienJen Chen,

MingWhei Yu

Publication year - 2005

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyi191

Subject(s) - xrcc1 , genotype , hepatocellular carcinoma , odds ratio , hepatitis b virus , allele , medicine , immunology , biology , cancer research , gastroenterology , single nucleotide polymorphism , gene , genetics , virus

Hepatitis B virus (HBV) induces hepatocellular carcinoma (HCC) mainly by causing chronic necroinflammatory hepatic disease. We investigated the mechanisms underlying the inflammatory hepatocarcinogenesis by examining whether genetic variations in cytokines, antioxidant enzymes, and DNA repair genes affect the HCC risk.

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