Case recruitment in genetic association studies: larger sample size or greater homogeneity? | Zendy

Chuen–Fei Chen | Zendy; WenChung Lee | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Case recruitment in genetic association studies: larger sample size or greater homogeneity?

Author(s) -

Chuen–Fei Chen,

WenChung Lee

Publication year - 2005

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyi086

Subject(s) - homogeneity (statistics) , sample size determination , association (psychology) , genetic association , statistics , biology , medicine , demography , genetics , psychology , mathematics , genotype , single nucleotide polymorphism , psychotherapist , gene , sociology

711 Graduate Institute of Epidemiology, College of Public Health, National Taiwan University, No. 1, Jen-Ai Road, 1st Section, Taipei, Taiwan. E-mail: wenchung@ha.mc.ntu.edu.tw In the previous example of cardiovascular diseases, suppose that the researcher has at his/her disposal, 300 patients with myocardial infarction (n1 = 300), 300 patients with stroke (n2 = 300), and 600 control subjects (n0 = 600). A literature search revealed that the allele frequencies are p1 = 0.158, p2 = 0.149, and p0 = 0.095, respectively. 1 Since

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research