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Quantitative evaluation of the effects of uncontrolled confounding by alcohol and tobacco in occupational cancer studies
Author(s) -
David Kriebel
Publication year - 2004
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyh151
Subject(s) - confounding , medicine , national health interview survey , environmental health , cohort study , cohort , demography , population , sociology
Uncontrolled confounding by personal exposures like smoking can limit the inferential power of occupational cohort studies. We developed and demonstrate a refinement of an existing type of sensitivity analysis, indirect adjustment, for evaluating the potential magnitude of confounding by alcohol and tobacco. Results of a large retrospective cohort study of laryngeal cancer and exposure to metalworking fluids (MWF) are used to illustrate the methods.

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