Effect of temperature and light on the stability of fat-soluble vitamins in whole blood over several days: implications for epidemiological studies | Zendy

Sarah J. Clark | Zendy

Open Access

Effect of temperature and light on the stability of fat-soluble vitamins in whole blood over several days: implications for epidemiological studies

Author(s) -

Sarah J. Clark

Publication year - 2004

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyh064

Subject(s) - epidemiology , medicine , physiology , food science , environmental health , biology

Biochemical measurement of fat-soluble vitamins would allow direct assessment in epidemiological studies of their association with disease. However, the perceived instability of these compounds and typically high cost of collection and analysis may make their measurement impractical, particularly in large-scale studies. Using a high performance liquid chromatography assay developed in-house, we have investigated the separate effects of temperature and light on the stability of vitamins in whole blood over several days.

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