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Relationship between birthweight and blood lipid concentrations in later life: evidence from the existing literature
Author(s) -
Liisa Laurén,
MarjoRiitta Järvelin,
Paul Elliott,
Ulla Sovio,
Anne Spellman,
Mark I. McCarthy,
Pauline Emmett,
Imogen Rogers,
AnnaLiisa Hartikainen,
Anneli Pouta,
Rebecca Hardy,
Michael Wadsworth,
Gunnhild Helmsdal,
Sjúrður F. Olsen,
Chryssa Bakoula,
Vasso Lekea,
Iona Y. Millwood
Publication year - 2003
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyg201
Subject(s) - medicine , environmental health , physiology , pediatrics
It has been suggested that there is a link between fetal growth and chronic diseases later in life. Several studies have shown a negative association between birthweight and cardiovascular diseases, as well as cardiovascular disease risk factors, such as blood pressure and type 2 diabetes. Far fewer studies have focused on the association between size at birth and blood lipid concentrations. We have conducted a qualitative assessment of the direction and consistency of the relationship between size at birth and blood lipid concentrations to see whether the suggested relationship between intrauterine growth and cardiovascular diseases is mediated by lipid metabolism.

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