The effects of alternative study designs on the power of community randomized trials: evidence from three studies of human immunodeficiency virus prevention in East Africa | Zendy

Jim Todd | Zendy; Lucy Carpenter | Zendy; Xianbin Li | Zendy; Jessica Nakiyingi | Zendy; Ron Gray | Zendy; Richard Hayes | Zendy

Open Access

The effects of alternative study designs on the power of community randomized trials: evidence from three studies of human immunodeficiency virus prevention in East Africa

Author(s) -

Jim Todd,

Lucy Carpenter,

Xianbin Li,

Jessica Nakiyingi,

Ron Gray,

Richard Hayes

Publication year - 2003

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyg150

Subject(s) - human immunodeficiency virus (hiv) , randomized controlled trial , medicine , virology , environmental health , immunology

Randomized intervention trials in which the community is the unit of randomization are increasingly being used to evaluate the impact of public health interventions. In the design of community randomized trials (CRT), the power of the study is likely to be affected by two issues: the matching or stratification of communities, and the number and size of the communities to be randomized.

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