
Mortality of hepatitis B surface antigen-positive blood donors in England and Wales
Author(s) -
Paul Crook,
Michael E. Jones,
Andrew Hall
Publication year - 2003
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyg039
Subject(s) - medicine , hbsag , population , hepatitis b , hepatitis b virus , carriage , liver disease , standardized mortality ratio , hepatocellular carcinoma , incidence (geometry) , epidemiology , immunology , pathology , virus , environmental health , physics , optics
Large population-based cohort studies in areas of high hepatitis B virus (HBV) prevalence have provided the evidence establishing hepatitis B surface antigen (HBsAg) carriage as a risk factor for hepatocellular carcinoma (HCC) and liver disease. Fewer studies have examined this in Western countries, where both HBV infection and carriage are less common and transmission patterns differ. This is the only prospective population-based study to examine this relationship in Europe.