Proton pump inhibitors and myocardial infarction: an application of active comparators in a self-controlled case series | Zendy

Celine Sze Ling Chui | Zendy; Ka Shing Cheung | Zendy; Jeremy Brown | Zendy; Ian Douglas | Zendy; Ian Chi Kei Wong | Zendy; Esther W. Chan | Zendy; Angel Wong | Zendy

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Proton pump inhibitors and myocardial infarction: an application of active comparators in a self-controlled case series

Author(s) -

Celine Sze Ling Chui,

Ka Shing Cheung,

Jeremy Brown,

Ian Douglas,

Ian Chi Kei Wong,

Esther W. Chan,

Angel Wong

Publication year - 2022

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyac196

Subject(s) - medicine , confidence interval , confounding , medical prescription , proton pump inhibitor , rate ratio , population , incidence (geometry) , pharmacology , physics , environmental health , optics

Previous studies investigating potential cardiovascular adverse events of acid-suppressing drugs are susceptible to protopathic bias and confounding. We aimed to investigate the association between short-term risk of myocardial infarction (MI) and proton pump inhibitors (PPIs) using a self-controlled case series (SCCS) with an active comparator.

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