Assessing the role of genome-wide DNA methylation between smoking and risk of lung cancer using repeated measurements: the HUNT study | Zendy

YiQian Sun | Zendy; Rebecca C. Richmond | Zendy; Matthew Suderman | Zendy; Josine L. Min | Zendy; Thomas Battram | Zendy; Arnar Flatberg | Zendy; Vidar Beisvåg | Zendy; Therese Haugdahl Nøst | Zendy; Florence Guida | Zendy; Lin Jiang | Zendy; Sissel Gyrid Freim Wahl | Zendy; Arnulf Langhammer | Zendy; Frank Skorpen | Zendy; Rosie M. Walker | Zendy; Andrew D. Bretherick | Zendy; Yanni Zeng | Zendy; Yue Chen | Zendy; Mattias Johansson | Zendy; Torkjel M. Sandanger | Zendy; Caroline L. Relton | Zendy; XiaoMei Mai | Zendy

Open Access

Assessing the role of genome-wide DNA methylation between smoking and risk of lung cancer using repeated measurements: the HUNT study

Author(s) -

YiQian Sun,

Rebecca C. Richmond,

Matthew Suderman,

Josine L. Min,

Thomas Battram,

Arnar Flatberg,

Vidar Beisvåg,

Therese Haugdahl Nøst,

Florence Guida,

Lin Jiang,

Sissel Gyrid Freim Wahl,

Arnulf Langhammer,

Frank Skorpen,

Rosie M. Walker,

Andrew D. Bretherick,

Yanni Zeng,

Yue Chen,

Mattias Johansson,

Torkjel M. Sandanger,

Caroline L. Relton,

XiaoMei Mai

Publication year - 2021

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyab044

Subject(s) - dna methylation , mendelian randomization , lung cancer , methylation , biology , cpg site , oncology , medicine , genetics , bioinformatics , dna , gene , genotype , gene expression , genetic variants

It is unclear if smoking-related DNA methylation represents a causal pathway between smoking and risk of lung cancer. We sought to identify novel smoking-related DNA methylation sites in blood, with repeated measurements, and to appraise the putative role of DNA methylation in the pathway between smoking and lung cancer development.

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