Paternal body mass index and offspring DNA methylation: findings from the PACE consortium | Zendy

Gemma C. Sharp | Zendy; Rossella Alfano | Zendy; Akram Ghantous | Zendy; José Urquiza | Zendy; Sheryl L. RifasShiman | Zendy; Christian M. Page | Zendy; Jianping Jin | Zendy; Sílvia FernándezBarrés | Zendy; Gillian Santorelli | Zendy; Gwen Tindula | Zendy

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Paternal body mass index and offspring DNA methylation: findings from the PACE consortium

Author(s) -

Gemma C. Sharp,

Rossella Alfano,

Akram Ghantous,

José Urquiza,

Sheryl L. RifasShiman,

Christian M. Page,

Jianping Jin,

Sílvia FernándezBarrés,

Gillian Santorelli,

Gwen Tindula

Publication year - 2020

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyaa267

Subject(s) - offspring , dna methylation , epigenome , body mass index , epigenetics , methylation , pregnancy , obesity , biology , genetics , physiology , medicine , endocrinology , gene , gene expression

Accumulating evidence links paternal adiposity in the periconceptional period to offspring health outcomes. DNA methylation has been proposed as a mediating mechanism, but very few studies have explored this possibility in humans.

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