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Being sceptical about meta-analyses: a Bayesian perspective on magnesium trials in myocardial infarction
Author(s) -
Julian P. T. Higgins,
David J. Spiegelhalter
Publication year - 2002
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/31.1.96
Subject(s) - myocardial infarction , skepticism , perspective (graphical) , meta analysis , medicine , bayesian probability , clinical trial , intensive care medicine , cardiology , psychology , epistemology , philosophy , computer science , artificial intelligence
There has been extensive discussion of the apparent conflict between meta-analyses and a mega-trial investigating the benefits of intravenous magnesium following myocardial infarction, in which the early trial results have been said to be 'too good to be true'.

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