Meta-analyses involving cross-over trials: methodological issues | Zendy

Diana R Elbourne | Zendy; Douglas G. Altman | Zendy; Julian P. T. Higgins | Zendy; François Curtin | Zendy; Helen V Worthington | Zendy; Andy Vail | Zendy

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Meta-analyses involving cross-over trials: methodological issues

Author(s) -

Diana R Elbourne,

Douglas G. Altman,

Julian P. T. Higgins,

François Curtin,

Helen V Worthington,

Andy Vail

Publication year - 2002

Publication title -

international journal of epidemiology

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/31.1.140

Subject(s) - meta analysis , randomized controlled trial , context (archaeology) , clinical trial , medicine , cochrane library , medline , medical physics , systematic review , cross over , surgery , pathology , paleontology , political science , law , biology

Meta-analysis of randomized controlled trials (RCTs) is usually based on trials where patients are randomized individually into two different, parallel, treatment groups. This paper concentrates on RCTs of a different design-two-period, two-treatment cross-over trials.

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