A mathematical model of hepatitis B virus transmission and its application for vaccination strategy in China | Zendy

Shoujun Zhao | Zendy; Zhiyi Xu | Zendy; Ying Lu | Zendy

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A mathematical model of hepatitis B virus transmission and its application for vaccination strategy in China

Author(s) -

Shoujun Zhao,

Zhiyi Xu,

Ying Lu

Publication year - 2000

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/29.4.744

Subject(s) - virology , vaccination , transmission (telecommunications) , hepatitis b virus , china , medicine , virus , immunology , computer science , geography , telecommunications , archaeology

Before universal infant immunization against hepatitis B virus (HBV) in 1986 China was a region endemic for HBV infection. The prevalence of HBV infection in the population was about 60% and the proportion of chronic HBV carriers around 10%. These HBV carriers could progress to chronic hepatitis B, cirrhosis, and primary hepatocellular carcinoma. Since 1976, large-scale sero-surveys of HBV infection have been carried out and a lot of data have been collected.

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