Longitudinal study of Plasmodium falciparum infection and immune responses in infants with or without the sickle cell trait | Zendy

JeanYves Le Hesran | Zendy; I. Personne | Zendy; P. Personne | Zendy; Nadine Fiévet | Zendy; Bertrand Dubois | Zendy; M. Beyeme | Zendy; Christian Boudin | Zendy; Michel Cot | Zendy; Philippe Deloron | Zendy

Open Access

Longitudinal study of Plasmodium falciparum infection and immune responses in infants with or without the sickle cell trait

Author(s) -

JeanYves Le Hesran,

I. Personne,

P. Personne,

Nadine Fiévet,

Bertrand Dubois,

M. Beyeme,

Christian Boudin,

Michel Cot,

Philippe Deloron

Publication year - 1999

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/28.4.793

Subject(s) - malaria , sickle cell trait , plasmodium falciparum , medicine , cohort , immunology , immune system , pediatrics , hemoglobin c , cohort study , antibody , hemoglobin , disease

Individuals may be homozygous (SS) or heterozygous (AS) sickle cell gene carriers or have normal adult haemoglobin (AA). Haemoglobin S could have a protective role against malaria but evidence is sparse and the operating mechanisms are poorly known.

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