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Increased risk of fatal prostate cancer may explain the rise in mortality in The Netherlands
Author(s) -
Piet N. Post,
Huub Straatman,
Lambertus A. Kiemeney,
J.W.W. Coebergh
Publication year - 1999
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/28.3.403
Subject(s) - medicine , prostate cancer , demography , incidence (geometry) , poisson regression , cohort , cancer , mortality rate , cohort effect , epidemiology , cohort study , subclinical infection , population , environmental health , physics , sociology , optics
Several lines of evidence suggest that, as a result of improved diagnostic techniques, the increase in incidence of prostate cancer is due largely to increased detection of subclinical cases. Between 1971 and 1989, a considerable increase in incidence was found in Southeastern Netherlands among men aged under 60 years without an improvement in prognosis. We hypothesized that in addition to the increase due to increased detection, a genuine increase in incidence has occurred in the last two decades and that this should be reflected in national mortality rates.

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